However, patients with chronic injury also develop liver cancer, opening the possibility that the stem cells are involved in tumor formation. 尽管如此,慢性肝损伤的患者也可以发展为肝癌,因为损伤加大了干细胞形成肿瘤的可能性。
Nuclear receptors are involved in regulating gene expression in development, cell proliferation differentiation and apoptosis, physiological, substance metabolism and tumor formation. 它们与机体的生长发育,细胞的增殖、分化与凋亡,以及体内众多生理、物质代谢及肿瘤形成过程中基因表达的调控有很大关系。
The alarm bell halts the process of cell division in its tracks, preventing an error that could lead to runaway cell division and eventually, tumor formation. 警报使细胞分裂停止,以防止可能引起细胞分裂失控&最终导致肿瘤形成的错误发生。
The Influence of mCD99L2~-A20 Cells and T Cells to Tumor Formation and Analysis of Biological Information mCD99L2~-A20细胞与T细胞对成瘤的影响及生物信息学分析
Activation of AMPK can suppress tumor formation and inhibit cell growth in addition to lowering blood glucose levels. AMP活化蛋白激酶的激活不但可降低血糖水平,而且可抑制肿瘤形成,阻止肿瘤细胞生长。
Cancer stem cells are the cause of tumor formation, recurrence and metastasis. 肿瘤干细胞是肿瘤形成、复发与转移的根源。
Effects of a Vascular Targeted Peptide ( GX1) on Tumor Formation and Angiogenesis and the Underlying Mechanisms 胃癌血管内皮靶向肽GX1在肿瘤生长及血管生成中的作用及机制研究
HRG is an activator of the HER-2 oncogene, promoting breast cancer growth and tumor formation in laboratory models. HRG是HER-2原癌基因的激动子,在动物模型中促进乳癌细胞的生长和肿瘤的形成。
The consensus that diets low in methionine and devoid of choline and folate are sufficient to independently induce tumor formation, primarily in the liver. 已经达成共识,低蛋氨酸或缺乏胆碱和叶酸的饮食足以独立地诱发肿瘤,以肝脏为主要靶点。
Neither endogenous nor exogenous TIMP-1 expression could influence the ability of tumor cloning formation and tumor formation. 内源性TIMP-1的表达有可能促使肿瘤细胞的移动能力增强;
Any pathogenesis interfering with proliferation-death mediating mechanism will induce excessive proliferation and/ or inhibition of apoptosis, result in abnormal cell accumulation and tumor formation. 当任何一种致病因素干扰了细胞增殖和/或凋亡的调控机制,导致细胞过度增殖和/或凋亡抑制,都会造成细胞的异常蓄积,以致形成肿瘤。
Background: Tumor suppressor gene negatively control cell growth, proliferation and differentiation. Loss of its functions caused by gene deletion and/ or mutation contribute to cell transformation and tumor formation. 背景:抑癌基因负性调节细胞的生长、增殖及分化,如果出现基因缺失、突变等异常使其功能丧失,则会导致细胞恶性转化而发生肿瘤。
Epithelial-mesenchymal transition ( EMT) occurs during critical phases of embryonic development in many animal species. It also play an important role in tumor formation and evolution. 上皮-间充质转变(EMT)是胚胎细胞在发育过程中重要的生物学行为,这一现象在肿瘤的形成与演进中也扮演了重要角色。
Four cases of Multiple Myeloma ( MM) with extramedullary tumor formation were presented. 本文报告4例多发性骨髓瘤伴有髓外肿块形成。
For the past few years, researchs in the metastasis mechanism of breast cancer reveal the important function of integrin-mediated signal in tumor formation, growth, invasion and metastasis. 近年来对乳腺癌转移机制研究显示:由整合素介导的细胞间及与细胞外基质的相互作用等信号事件在乳腺肿瘤形成、生长、侵袭、转移诸多过程中起了重要作用。
Memory CTL needs T H cells to completely regress the development of tumor formation. 记忆性CTL的完全抑瘤活性需要抗原特异性TH细胞的辅助。
The proliferation of HeLa cells in vitro and in vivo was determined by clone formation assay, MTT assay, and subcutaneous tumor formation in nude mice. 克隆形成实验、MTT法和裸鼠皮下瘤形成实验分别检测细胞克隆形成率及细胞在体外和体内的增殖情况。
Reducing the expression of Survivin gene will help to inhibit normal cell proliferation and reverse tumor formation. 通过调低该基因的表达有助于抑制细胞增殖,逆转肿瘤形成。
Persistent activation of G-CSF signaling induces tumor formation in hematopoietic system. 造血干细胞中G-CSF信号通路持续过度激活可导致血液系统肿瘤的发生。
After using antisense technology to reduce cells expression of OPN, the cell survival rate in soft agar decline, so as to the rate of nude mice tumor formation and the ability of distant metastasis. 用反义核酸技术降低细胞中OPN的表达后,细胞软琼脂生存率下降,裸鼠成瘤率和发生远处转移的能力降低[28]。
Lung adenocarcinoma stem cells proliferated obviously and posseses the ability of tumor formation. 3. 分离的肺腺癌干细胞具有较强的增殖能力和致瘤能力。
Detection of tumor formation rate in nude mice post inoculation. 检测裸鼠接种后的成瘤率。
Precancerous injuries of BRL cells could cause the microenvironment change, which can enhance the ability of tumor formation, migration and invasion. BRL细胞非致瘤性损伤可改变微环境,从而增强肿瘤细胞的成瘤、迁徙和侵袭能力。
Record the time of tumor formation, size, morphology, texture and activity. 记录成瘤时间并计算成瘤率,观察移植瘤大小、形态、质地及活动度。
Also ADAMs has been reported to play an important role in tumor formation, invasion and metastasis in both animal models and cancer patients. 既然ADAMs家族基因已经被报道在动物模型和癌症患者中肿瘤的形成、侵袭和转移中占有重要的一席之地。
To construct an osteosarcoma in situ tumor formation and pulmonary metastasis model, and then evaluate the effects of miR-34a on the capacities of in situ tumor formation and pulmonary metastasis. 4. 构建裸鼠的骨肉瘤原位成瘤肺转移模型,并进一步研究miR-34a对骨肉瘤细胞原位成瘤能力和肺转移能力的影响。
Not only the transplantation of ESC but also the transplantation of ESC-derived differentiated cells would result in the tumor formation. 不仅是ESC的移植会导致肿瘤的生成,ESC来源的分化细胞移植也可能会有肿瘤形成的风险。
Recently, the research that BLyS is relevant to human immunologic diseases especially to B cell tumor formation and development is still in the starting stage. This kind of research has been becoming a new focus as the diagnosis and treatment of immunologic diseases. 目前关于BLyS与人免疫性疾病,尤其是与B细胞恶性肿瘤形成和发展关系的研究尚处于起步阶段,正成为其诊断和治疗研究的一个新热点。
Through the tumor-bearing mice models, we found that the tumor formation were affected by BEAL which had an effect obvious on anti-tumor under a certain conditions. 4. 通过荷瘤小鼠模型,发现BEAL影响了肿瘤的形成,在一定条件下具有明显的抑瘤作用。
And in vivo, miR-34a also remarkably inhibits the capacities of in situ tumor formation and pulmonary metastasis. 4. 动物实验中,miR-34a对骨肉瘤的原位成瘤能力和肺转移能力同样有显著的抑制作用。